SERVICE
Discover the world’s first blood-based test that identifies your personalized optimal embryo transfer window.
ora™ analyzes microRNAs (miRNA) in the blood using next-generation sequencing (NGS) to determine the endometrium’s receptive period for implantation.
The WOI refers to the period within the menstrual cycle when the endometrium is most receptive to embryo implantation. Since this window can vary from person to person, a personalized test is essential.
Non-Invasive
Non-Invasive
Blood-based test (safe and simple)
Single Cycle
Single Cycle
Only one test required
High Accuracy
High Accuracy
More than 95% accuracy
Less than 1% retest rate
Comprehensive Analysis
Comprehensive Analysis
Assessment of 281 miRNA biomarkers
To prevent repeated implantation failure, a personalized embryo transfer (pET) is necessary.
* pET : personalized Embryo Transfer
Around 30% of women have a window of implantation (WOI) that is either earlier or later than average. As a result, implantation may fail even when high-grade embryos are transferred.
The non-invasive endometrial receptivity analysis is recommended for
Conventional tissue test | ora™ test | |
---|---|---|
Type | Invasive | Non-invasive |
Specimen | Endometrial tissue | Blood |
Biomarkers | mRNA (messengerRNA) | miRNA (microRNA) |
Method | qPCR or NGS | NGS |
Convenience | Low | High |
Specimen collection method Endometrial biopsy |
discomfort, burden, recovery from pain, delayed embryo transfer | convenient, simple, no discomfort |
Failure rate | High (in cases of thin endometrium or insufficient sample) | Low (less than 1%) |
*Inconclusive : ora™ algorithm could not analyze the result data. Re-sampling of the patient’s blood is required.
*Invaild/Insufficient RNA : The RNA quality or concentration of the blood sample was inadequate for ora™ testing. Re-sampling of the patient’s blood is required.
Blood sample
Secure delivery by a certified courier service
Next-generation sequencing (NGS) analysis
Identification of the window of implantation (WOI)
Test name | Non-invasive endometrial receptivity test (ora™, non-invasive Optimal Receptivity Analysis) |
---|---|
Method | Next-generation sequencing (NGS) (NGS, Next Generation Sequencing) |
Test items | 281 miRNAs |
Testing period | HRT : Blood draw on Day 4 or Day 5 after progesterone administration Natural Cycle : Blood draw on Day 6 or Day 7 after LH surge or hCG trigger shot |
Specimen information | Specimen type : Whole blood Volume : 5ml ~ 10ml |
Turnaround time | 3 weeks (business days) |
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