SERVICE
Preimplantation Genetic Testing (PGT) involves retrieving a few cells from embryos on day 3 or days 5–7 after in vitro fertilization (IVF). The DNA is amplified and analyzed using next-generation sequencing (NGS) to detect chromosomal abnormalities.
By selecting and transferring genetically normal embryos through PGT, the chances of achieving a successful pregnancy with IVF can be significantly improved.
High accuracy
Minimal sample required
High sensitivity
Faster turnaround time
As of the first half of 2024, available at more than 52 hospitals nationwide
Day 3 embryo (Blastomere)
1~2 cells
Day 5–7 embryo (Trophectoderm)
5–10 cells
GenoBro
Dedicated PCR tube
For an embryo created through IVF to successfully implant and sustain a pregnancy, not only its appearance but also its chromosomes must be normal.
Embryos with chromosomal abnormalities are more likely to fail implantation or cause recurrent miscarriage. In addition, as maternal age increases, the proportion of genetically normal embryos decreases.
To improve implantation rates and reduce the risk of miscarriage, it is essential to select chromosomally normal embryos for transfer through preimplantation testing.
Embryo biopsy (embryo cells)
Secure delivery by a certified courier service
Next-generation sequencing (NGS) analysis
Detection of chromosomal abnormalities in embryos
| Test name | GenoBro (Preimplantation Genetic Testing, PGT) |
|---|---|
| Method | Next-generation sequencing (NGS) (NGS, Next Generation Sequencing) |
| Test items | PGT-A: Screening for numerical chromosomal abnormalities in embryos PGT-SR: Screening for structural chromosomal abnormalities in embryos |
| Testing period | Day 3 or Days 5–7 of in vitro embryo culture |
| Specimen information | Day 3 embryo: blastomere cells (partial sample) Days 5–7 embryo: trophectoderm cells (partial sample) |
| Submission deadline | By 12:00 p.m. (noon) |
| Turnaround time | Next business day (if received before 12:00 p.m.) Two business days later (if received after 12:00 p.m.) |
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