Service Introduction
 
PGS(Pre-implantation Genetic Screening)
 
 
 
GenoBro is an NGS-based PGS(pre-implantation screening) test that selects genetically normal embryos. It has a much higher sensitivity and suspend time than conventional methods (FISH, aCGH) and can shorten inspection time.
Increased implantation and pregnancy success rates and elimination of embryos with chromosomal abnormalities can reduce abortion rate.
 

GenoBro is Pre-implantation genetic screening
    base on NGS(Next-Generation Sequencing),
    it is a fast and accurate screening in order to select genetically normal embryos.

 

1. What is NGS?

 
 

Preimplantation genetic screening (PGS) for aneuploidy is a powerful genetic test that may be performed on embryos during IVF treatment to screen for numerical chromosomal abnormalities. PGS is performed on a small embryo biopsy prior to transfer and identifies which embryos are chromosomally normal. Chromosomally normal embryos are the most likely to develop to term and to be born as a healthy baby. PGS testing helps IVF physicians and patients decide which embryos to transfer.

2. Inspection Principle

 
After the in vitro fertilization, the embryo is harvested from 3 to 5 days after the amplification of the DNA, and then analyzed by using the next generation genome sequencing technology, which is the latest analysis technology, to analyze the chromosome abnormality more quickly and accurately. Because of this principle, the Embryos with normal chromosomes can be screened

3. Who is a Candidate?

4. Undergoing Procedure

 

5. Proven normal detection rate from Clinical Test

 
According to the results of many overseas papers and clinical studies of famous international IVF centers, the proportion of normal embryos will decrease as the patient ages. In the range of 35 to 40 years old, blastomere (3rd day of embryo) stage is 20 to 30%, Blastocyst (5th day of Embryo) stage is 40 to 50%, those data are normal embryo detection rate and it is an international standard.
However, there are differences in the percentage of normal embryos depending on the individual characteristics of the patient and the status and stage of the embryo.
 

6. Advantages of NGS-based PGS

 
With the latest NGS equipment, inspection time can be shortened and accurate inspection is possible even with small amount of sample.  

 

 

 

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